What are the symptoms of cholestasis?
Cholestasis is a disease caused by an obstruction in the flow or decreased secretion of bile, which may be caused by problems with the liver, bile ducts, or gallbladder. In recent years, with the popularization of health science, the symptoms and treatment of cholestasis have become a hot topic of public concern. The following is a detailed symptom analysis of cholestasis, presented with structured data.
1. Common symptoms of cholestasis
Symptoms of cholestasis vary depending on the cause and severity, but generally include the following:
| Symptom type | Specific performance |
|---|---|
| skin symptoms | Skin itching (especially worse at night), jaundice (yellowing of the skin and sclera) |
| digestive symptoms | Loss of appetite, nausea, vomiting, steatorrhea (greasy and foul-smelling feces) |
| systemic symptoms | Fatigue, weight loss, darker urine (tea-colored urine) |
| Other symptoms | Right upper quadrant pain (may radiate to the back), vitamin K deficiency leading to bleeding tendency |
2. Classification of causes of cholestasis
Cholestasis can be divided into intrahepatic and extrahepatic types, with different causes and slightly different symptoms:
| Type | Common causes |
|---|---|
| intrahepatic cholestasis | Viral hepatitis, drug-induced liver injury, cholestasis of pregnancy, primary biliary cholangitis |
| extrahepatic cholestasis | Common bile duct stones, bile duct stricture, tumor compression (such as pancreatic cancer) |
3. High-risk groups and complications
The following groups of people need to be alert to the occurrence of cholestasis and pay attention to possible complications:
| high risk groups | potential complications |
|---|---|
| chronic drinker | Cirrhosis, liver failure |
| Pregnant women (late pregnancy) | Premature birth, fetal distress |
| Patients with a history of gallstones | Cholangitis, pancreatitis |
4. Diagnosis and treatment suggestions
If the above symptoms occur, it is recommended to seek medical treatment in time. The doctor may confirm the diagnosis through the following methods:
1.Laboratory tests:Liver function test (ALT, AST, ALP elevation), bilirubin level assessment.
2.Imaging examination:Ultrasound, CT or MRCP (magnetic resonance cholangiopancreatography) to observe the bile duct structure.
3.Liver biopsy:Some cases require biopsy to determine the cause.
Treatment needs to target the cause, such as:
5. Recent hot topics
Recently, discussions about cholestasis have focused on:
1.Health science:The topic "Jaundice and Liver Disease" has been read more than 10 million times on social media, reminding the public to pay attention to early symptoms.
2.Research progress:The effect of the new drug Obeticholic Acid on primary biliary cholangitis has attracted attention.
3.Patient stories:A warning has been raised about cholestasis in pregnancy after a pregnant woman ignored her itching symptoms and put her fetus at risk.
Through structured data and detailed analysis, we hope to help readers have a clearer understanding of the symptoms and countermeasures of cholestasis. If relevant symptoms occur, be sure to seek medical treatment promptly to avoid delays in treatment.
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