What medicine should you not take if you have liver disease?
The liver is an important metabolic organ in the human body and is responsible for detoxification, drug metabolism and other functions. For patients with liver disease, the liver function has been damaged, so they need to be extra cautious when taking medications to avoid increasing the burden on the liver or causing drug-induced liver injury. The following are drugs and precautions that patients with liver disease should avoid or use with caution.
1. Drugs that patients with liver disease should avoid

| drug class | specific drugs | Potential risks |
|---|---|---|
| antipyretic analgesics | Acetaminophen (paracetamol), aspirin | Excessive use may cause liver cell necrosis |
| antibiotics | Erythromycin, tetracycline, isoniazid | May cause drug-induced hepatitis |
| antifungal drugs | Ketoconazole, fluconazole | May worsen liver damage |
| antituberculosis drugs | Rifampicin, pyrazinamide | May cause hepatotoxicity |
| antiepileptic drugs | Sodium valproate, carbamazepine | May cause elevated liver enzymes |
| Traditional Chinese medicine and health products | Polygonum multiflorum, tripterygium wilfordii, certain weight loss drugs | Some Chinese medicines may contain hepatotoxic ingredients |
2. Medication precautions for patients with liver disease
1.Avoid self-medication: Patients with liver disease should take medication under the guidance of a doctor and never buy or take medications by themselves, especially over-the-counter medications.
2.Monitor liver function regularly: Patients who take medicine for a long time need to check their liver function regularly to detect the impact of the medicine on the liver in a timely manner.
3.Be aware of drug interactions: The combined use of some drugs may increase liver toxicity. You need to inform your doctor of all the drugs you are taking.
4.Adjust medication dosage: Patients with hepatic impairment may require reduced drug dosage or extended dosing intervals.
3. Medication recommendations for patients with liver disease
| Symptoms | Optional medications | Things to note |
|---|---|---|
| Fever/pain | Ibuprofen (short-term, low-dose) | Avoid long-term use and monitor liver function |
| high blood pressure | Amlodipine, Irbesartan | Choose antihypertensive drugs with less hepatotoxicity |
| diabetes | Insulin, gliclazide | Avoid antidiabetic drugs that may damage the liver |
| infection | Penicillins, cephalosporins | Give priority to antibiotics with low hepatotoxicity |
4. Daily suggestions for protecting the liver
1.diet conditioning: Eat more high-protein, low-fat foods, avoid greasy and spicy foods, quit smoking and limit alcohol consumption.
2.Regular schedule: Ensure adequate sleep, avoid staying up late, and reduce the burden on the liver.
3.moderate exercise: Choose appropriate exercise methods according to your physical condition to enhance your physical fitness.
4.Emotional management: Maintain a good attitude and avoid excessive anxiety and stress.
5. Summary
Patients with liver disease need to be extra cautious when taking medications and avoid drugs that may damage the liver. When choosing a drug, you should consult a professional doctor to weigh the pros and cons. At the same time, protect liver function through a healthy lifestyle, regularly monitor liver function indicators, and detect and deal with problems in a timely manner. Remember, proper medication use and healthy living are the keys to protecting your liver.
If symptoms such as fatigue, loss of appetite, and jaundice occur, you should seek medical attention immediately to check whether it is related to the drug. Patients with liver disease should establish their own medication files to record all the drugs they have taken and their reactions to provide reference for subsequent treatment.
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